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The two volumes of Bioarchaeology of the Southwest bring together more than 100 years of research into the lives of the ancient people of the Southwest United States and Northwest Mexico. Volume 2 contains chapters that include northern and southern Arizona, southwest New Mexico, and northern Mexico.

This volume examines how Mexican populations have been shaped both culturally and biologically by European colonization, drawing on methods from archaeology, bioarchaeology, genetics, and history and providing evidence for the resilience of the Mexican people in the face of tumultuous change.